Empilweni, kuyenzeka ukuthi isandla sinqunywe ngephutha futhi igazi lingami. Umfanyana wakwazi ukuyeka ukopha ngemva kwemizuzwana embalwa ngosizo lwe-gauze entsha ukuze ayeke ukopha. Ingabe kuyamangalisa ngempela?
Inoveli ye-chitosan arterial hemostatic gauze iyeka ukopha ngaso leso sikhathi
Igazi liwumthombo wokuphila, futhi ukulahlekelwa igazi eliningi kuyimbangela ehamba phambili yokufa ngenxa yokulimala ngengozi. Emhlabeni wonke, kufa abantu abayizigidi ezingu-1,9 unyaka ngamunye ngenxa yokulahlekelwa igazi eliningi. “Uma umuntu enesisindo esingamakhilogremu angu-70, umthamo wegazi lomzimba uthatha cishe u-7% wesisindo somzimba, okungukuthi, u-4,900 ml, uma ukulahlekelwa igazi lingaphezu kuka-1 000 ml ngenxa yokulimala ngengozi, kuyingozi empilweni.” Kodwa lapho usizo lwezokwelapha lufika, usizo lokuqala oluvamile luwukumboza isilonda ngamathawula, izingubo, njll., okungase kusebenze lapho umthambo noma i-capillary ukopha, kodwa uma umthambo wopha, izindlela ezinjalo zokopha ngokuvamile azanele.”
Ekwelashweni okuphuthumayo kwangaphambi kwesibhedlela, ukulawula okusebenzayo ukopha kweziguli ngesikhathi sokuqala kuyisihluthulelo sokuthola isikhathi sokwelashwa nokusindisa izimpilo.
Muva nje, i-chitosan arterial hemostatic gauze entsha esheshayo ibidumile emakethe. Le gauze inezinhlayiya eziyingqayizivele ze-chitosan.Ama-Chitosan granules ahlanganiswe ne-high-density gauze evumela ukupakisha okusheshayo nokunamathela okukhulu kwezicubu ezizungezile. Ama-Chitosan granules anamathela esicutshini esimanzi esilondeni, athuthukisa umphumela we-tamponade we-gauze futhi alawule ukulahleka kwegazi.
Inqubo ye-hemostatic eyingqayizivele
Imunca amanzi egazini futhi yakhe ijeli ehlanganisa amangqamuzana abomvu egazi ukuze enze ihlule legazi. Ukuze umise ukopha ngo-100%, beka ngokucophelela ingxenye yebhandeshi le-hemostatic emgodini wenxeba, vala (tampon) bese ubamba, ucindezela ngezandla zakho. , imizuzu emi-5. Ngalesi sikhathi, igazi lizogcwalisa ibhandishi, ama-chitosan granules acushiwe, avuvuke futhi aphenduke abe ijeli eliwugqinsi. Ubuningi bejeli buzovala isitsha esophayo, bumise ukopha, bese kwakheka ijeli yokuvala isilonda. Ngesikhathi esifanayo, i-chitosan ibopha namangqamuzana egazi abomvu ukuze ikhiqize ama-gel, angavimbela ngokuphumelelayo ukungcoliswa kwesibili kwebhaktheriya kwesilonda.
Le gauze ye-hemostatic ingalawula ngokushesha ukopha okusesilinganisweni nokubi okubangelwa ukuhlukumezeka, kuhlanganise nokulawula okuphumelelayo komthambo omkhulu wegazi phakathi nemizuzu emithathu, futhi ngeke kukhiqize ukushisa. Ngaphezu kokufaneleka ukopha okujulile komthambo, ingase isetshenziselwe amanxeba angaphandle. Indawo yesilonda ayinqunyelwe, futhi ikhanda, intamo, isifuba, isisu nezinye izingxenye zomzimba zingasetshenziswa ngokuphepha. I-gauze ye-hemostatic inamathela ngokuqinile esilondeni, inciphisa ingozi yamagciwane atholakala egazini, futhi ihlala endaweni lapho isisulu sihanjiswa, kuvimbela ukopha kwesibili. Amahlule egazi angakwazi ukujiya kungakapheli imizuzu embalwa ethele esilondeni, futhi ihlule lilula kakhulu ukulikhipha futhi lingagezwa kalula ngamanzi noma ngosawoti. Indlela yokusebenza yale gauze ye-hemostatic ayincikile ku-coagulation factor egazini, ngakho-ke iyasebenza egazini le-heparinized. Uma kubhekwa ukuvuza koketshezi lokugaya okubangelwa ukulimala okungena ngaphakathi, le gauze ye-hemostatic ingaba neqhaza ekuvimbeni umgudu wokuvuza futhi ivimbele uketshezi lokugaya ekulimaleni kwesibili emzimbeni. I-hemostasis efika ngesikhathi futhi ephumelelayo iphinde inciphise ukulahlekelwa uketshezi lomzimba, inciphise ukuvela kokushaqeka, ivikele ngokuphumelelayo isilonda, futhi igweme ukulimala kabusha kwezicubu.
Ngaphezu kwalokho, i-gauze ye-hemostatic ayithinteki ekushiseni kwe-ambient futhi isasebenza kahle ekushiseni kwegazi kwe-18.5 ° C. Isikhathi seshelufu siyiminyaka emi-5 futhi azikho izimo ezikhethekile zokulondoloza ezidingekayo. Ukusebenzisa amaphakethe angangeni manzi oyinyumba, kulula ukukuthwala, kulula ukusebenza, imiyalelo yokufaka okungeyona eyochwepheshe nayo ingasebenza ngokushesha. Kungokwemvelo, kuhlanjululwe kakhulu, akukho ukusabela okweqile emlandweni wokusetshenziswa, akuyona into enobuthi, i-non-carcinogenic, ne-non-immunogenic. I-deep-sea chitosan etholakala ku-deep-sea krill endaweni ephakeme ihlanzwa isilinganiso segolide, enezinga legolide le-deacetylation, okuqukethwe kwensimbi esindayo ephansi kanye nomlotha ophansi. Izinhlayiya ze-hemostatic ezinomphumela wokuhlanzeka okuphezulu ziyi-polysaccharides yebhayoloji okulula ukuyihlanza, akukho mkhuba we-turbidity, futhi ayizinto ezibolayo.
Isikhathi sokuthumela: Oct-08-2023